Sonodynamic Therapy Decreased Neointimal Hyperplasia After Stenting in the Rabbit Iliac Artery
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چکیده
منابع مشابه
Sonodynamic therapy decreased neointimal hyperplasia after stenting in the rabbit iliac artery.
BACKGROUND In-stent restenosis remains a pivotal problem after coronary and peripheral stenting. Sonodynamic therapy inhibits tumor growth by means of cytotoxicity after the activation of sonochemical sensitizers by ultrasound. PAD-S31 is known to be a water-soluble, chlorin-derivative sonochemical sensitizer. We assessed the efficacy of sonodynamic therapy using this sensitizer on neointimal h...
متن کاملLow molecular weight fucoidan prevents neointimal hyperplasia in rabbit iliac artery in-stent restenosis model.
OBJECTIVE Smooth muscle cell (SMC) proliferation within the intima is regulated by heparan sulfates. We studied a low molecular weight (LMW) fucoidan (sulfated polysaccharide from brown seaweed) on SMC proliferation in vitro and intimal hyperplasia in vivo. METHODS AND RESULTS In vitro study revealed that LMW fucoidan reduces rabbit SMC proliferation and is internalized in SMC perinuclear ves...
متن کاملLow Molecular Weight Fucoidan Prevents Neointimal Hyperplasia in Rabbit Iliac Artery
Jean-François Deux, Anne Meddahi-Pellé, Alain F. Le Blanche, Laurent J. Feldman, Sylvia In-Stent Restenosis Model Low Molecular Weight Fucoidan Prevents Neointimal Hyperplasia in Rabbit Iliac Artery Print ISSN: 1079-5642. Online ISSN: 1524-4636 Copyright © 2002 American Heart Association, Inc. All rights reserved. Greenville Avenue, Dallas, TX 75231 is published by the American Heart Associatio...
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An 82-year-old man was referred to the nephrology division due to a sudden increase in creatinine (from 0.7 to 1.6 mg/dL). Two months earlier, the patient had undergone endovascular treatment with stent implantation (WALLSTENT Endoprosthesis, Boston Scientific, Natick, USA) in the left common iliac artery for peripheral artery disease. A CT scan revealed left hydronephrosis (Picture 1). Dilatio...
متن کاملAlterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries.
Restenosis resulting from neointimal hyperplasia (NH) limits the effectiveness of intravascular stents. Rates of restenosis vary with stent geometry, but whether stents affect spatial and temporal distributions of wall shear stress (WSS) in vivo is unknown. We tested the hypothesis that alterations in spatial WSS after stent implantation predict sites of NH in rabbit iliac arteries. Antegrade i...
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ژورنال
عنوان ژورنال: Circulation
سال: 2002
ISSN: 0009-7322,1524-4539
DOI: 10.1161/hc0202.102921